Preventive bundle approach decreases the incidence of ventilator associated pneumonia in newborn infants Journal of Perinatology VAP Bundle Ventilator Associated Pneumonia Ventilator Associated Pneumonia ( VAP) is a lung infection that occurs in patients who are on mechanical ventilation for more than 48 hours. A VAP bundle is a set of Optimizing Ventilator Associated Pneumonia Prevention and Education: I" by Danielle Gonzalez VAP Guideline Review The Vexing Problem of Ventilator Associated Pneumonia: Observations on Pathophysiology, Public Policy, and Clinical Science Richard H Kallet, 2015