Melanotan II Safety: Tanning Injection LIVV Natural Is It Safe to Get a Fake (Sunless) Tan? Spray Tans Tanning Pills American Cancer Society Your body already makes a hormone that tells your skin to tan. Melanotan 2 is a synthetic peptide engineered to mimic that hormone but in a version that's more potent and You may have heard about the latest trend tanning nasal sprays and injections. So how does it work and is it safe? Refs: Fjellhaugen Hjuler et al., 2014, Melanoma associated with the use of Melanotan II (Tan Jabs): Why They're Not Worth The Risk