Could Tylenol be making your child's health worse? Acetaminophen is widely used for pain and fever relief, but research suggests it depletes glutathione, a powerful antioxidant essential for immune function, Tylenol depletes something called glutathione. Glutathione is a master antioxidant and your first line of protection against environmental toxins. It detoxifies and protects your cells. It protects your immune system and Acetaminophen Toxicity: How Genetic Susceptibility Combines with Environmental Factors Tylenol And Alcohol: Dangers, Safe Alternatives & Treatment When Good Drugs Go Bad: Acetaminophen Toxicity tl;dr pharmacy