Long COVID Chan Soon Shiong Institute for Medicine If fatigue, brain fog, or crashes make everything feel harder, strengthening the basics can make a real difference. Supporting mitochondrial function is a core piece of many Long COVID and ME CFS treatment Long COVID is not just viral. It's oxidative and inflammatory. Research suggests that low glutathione levels and excess oxidative stress play a major role in long COVID symptoms like fatigue, brain Long COVID post viral chronic fatigue and affective symptoms are associated with oxidative damage, lowered antioxidant defenses and inflammation: a proof of concept and mechanism study Molecular Psychiatry Persistent Post COVID 19 Endothelial Dysfunction and Oxidative Stress in Women